Collaborations & Alliances

Allergan, AstraZeneca in Global Antibiotic Pact

Will evaluate aztreonam and avibactam combo in Gram-negative infections

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By: Kristin Brooks

Managing Editor, Contract Pharma

Allergan has entered into a global agreement with AstraZeneca to develop and commercialize ATM-AVI, an investigational, fixed-dose antibiotic combining aztreonam and avibactam. The companies will evaluate the combination to treat serious infections caused by metallo βlactamase MBL-producing Gram-negative pathogens, a difficult-to-treat sub-type of carbapenem-resistant Enterobacteriaceae (CRE), for which there are limited treatments. Allergan will maintain commercialization rights in the U.S. and...

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